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Article

Constraint-based modeling identifies new putative targets to fight colistin-resistant A. baumannii infections.

Scientific reports - 16 Jun 2017

Presta Luana, Bosi Emanuele, Mansouri Leila, Dijkshoorn Lenie, Fani Renato, Fondi Marco

Abstract excerpt

Acinetobacter baumannii is a clinical threat to human health, causing major infection outbreaks worldwide. As new drugs against Gram-negative bacteria do not seem to be forthcoming, and due to the microbial capability of acquiring multi-resistance, there is an urgent need for novel therapeutic targets. Here we have derived a list of new potential targets by means of metabolic reconstruction and modelling of A....

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Identifiers

PMID: 28623298
DOI: 10.1038/s41598-017-03416-2
PMCID: PMC5473915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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