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Article

Reconstructing organisms in silico: genome-scale models and their emerging applications.

Nature reviews. Microbiology - 1 Dec 2020

Fang Xin, Lloyd Colton J, Palsson Bernhard O

Abstract excerpt

Escherichia coli is considered to be the best-known microorganism given the large number of published studies detailing its genes, its genome and the biochemical functions of its molecular components. This vast literature has been systematically assembled into a reconstruction of the biochemical reaction networks that underlie E. coli's functions, a process which is now being applied to an increasing number of...

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Identifiers

PMID: 32958892
DOI: 10.1038/s41579-020-00440-4
PMCID: PMC7981288

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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