Article
Calbindin independence of calcium transport in developing teeth contradicts the calcium ferry dogma.
The Journal of biological chemistry - 31 Dec 2004
Turnbull Chris I, Looi Ken, Mangum Jonathan E, Meyer Michael, Sayer Rod J, Hubbard Michael J
Abstract excerpt
Cytosolic calcium-binding proteins termed calbindins are widely regarded as a key component of the machinery used to transport calcium safely across cells. Acting as mobile buffers, calbindins are thought to ferry calcium in bulk and simultaneously protect against its potentially cytotoxic effects. Here, we contradict this dogma by showing that teeth and bones were produced normally in null mutant mice lacking...
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