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Article

Normalisation of calcium status reverses the phenotype in dentin, but not in enamel of VDR-deficient mice.

Archives of oral biology - 1 Dec 2009

Zhang Xueming, Rahemtulla Firoz, Zhang Ping, Li Xingsheng, Beck Preston, Thomas Huw F

Abstract excerpt

OBJECTIVE: To determine the effects of vitamin D receptor (VDR) deficiency on mouse dentin and enamel mineralisation, and how normalisation of serum calcium level affects dentin and enamel phenotypes in VDR knockout mice. MATERIALS AND METHODS: Groups of VDR wild-type (VDR+/+), VDR deficient (VDR-/-) and VDR-/- rescued mice were sacrificed at 70.5 days of life. The rescued group was established by a high-calcium...

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Source

Identifiers

PMID: 19850279
DOI: 10.1016/j.archoralbio.2009.09.004

Genes

VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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