Article
Physiopathology of dental rickets in vitamin D receptor-ablated mice.
Journal of dental research - 1 Dec 2010
Descroix V, Kato S, Lézot F, Berdal A
Abstract excerpt
1α25(OH)(2)vitaminD(3) and its nuclear receptor, VDR, are essential for normal tooth development. However, the relative contributions of the direct vs. indirect effects of vitamin D action on odontogenesis are unclear. The aim of this study was to discriminate among the specific roles of 1α25(OH)(2) vitaminD(3), calcemia/phosphatemia, and the maternal environment in mouse VDR null mutants. Microradiographic,...
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