Article
Phenotype of a calbindin-D9k gene knockout is compensated for by the induction of other calcium transporter genes in a mouse model.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Dec 2007
Lee Geun-Shik, Lee Kun-Yeong, Choi Kyung-Chul, Ryu Young-Han, Paik Sang Gi, Oh Goo Taeg, Jeung Eui-Bae
Abstract excerpt
UNLABELLED: CaBP-9k may be involved in the active calcium absorption and embryo implantation. Although we generated CaBP-9k KO mice to explore its function, no distinct phenotypes were observed in these KO mice. It can be hypothesized that TRPV5 and 6 and plasma membrane calcium ATPase 1b may play a role in the regulation of calcium transport to compensate CaBP-9k deficiency in its KO model. INTRODUCTION: Active...
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