Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aberrant methylation of p57KIP2 gene in lung and breast cancers and malignant mesotheliomas

1 Nov 2004

Abstract excerpt

The p57KIP2 gene belongs to the Cip/Kip family of CDK inhibitors and has been demonstrated to be a tumor suppressor gene, being inactivated in various types of human cancers. We analyzed the methylation and expression status of p57KIP2 in lung and breast cancers, and in malignant mesotheliomas (MMs). The promoter region of p57KIP2 was determined by methylation-specific PCR (MSP) in samples of lung and breast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Metastasis and carcinoma case studies
Share to Occupational and environmental lung diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15492797
DOI: 10.3892/or.12.5.1087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aberrant methylation of p57KIP2 gene in lung and breast cancers and malignant mesotheliomasPMID 15492797Read ↗

Epigenetic Profiles Distinguish Malignant Pleural Mesothelioma from Lung AdenocarcinomaSemantic proximity Read ↗

p57Kip2 and Cancer: Time for a Critical AppraisalSemantic proximity Read ↗

Repression of MAL tumour suppressor activity by promoter methylation during cervical carcinogenesisSemantic proximity Read ↗

Aberrant p27Kip1 promoter methylation in malignant melanoma.Semantic proximity Read ↗

CDKN1C/p57kip2is a candidate tumor suppressor gene in human breast cancerSemantic proximity Read ↗

Immunohistochemical Analysis of the p16INK4 Cyclin-Dependent Kinase Inhibitor in Malignant MesotheliomaSemantic proximity Read ↗

Epigenetic inactivation of the CIP/KIP cell-cycle control pathway in acute leukemias.Semantic proximity Read ↗

Frequent Inactivation of RAMP2, EFEMP1 and Dutt1 in Lung Cancer by Promoter HypermethylationSemantic proximity Read ↗

Epigenetic Silencing of MicroRNA-34b/c Plays an Important Role in the Pathogenesis of Malignant Pleural MesotheliomaSemantic proximity Read ↗

Epigenetic Down-Regulation of <i>CDKN1C/p57KIP2</i> in Pancreatic Ductal Neoplasms Identified by Gene Expression ProfilingSemantic proximity Read ↗

Aberrant promoter methylation of WIF-1 and SFRP1, 2, 4 genes in mesotheliomaSemantic proximity Read ↗

Inactivation of p16INK4a expression in malignant mesothelioma by methylationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.