Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic Down-Regulation of <i>CDKN1C/p57KIP2</i> in Pancreatic Ductal Neoplasms Identified by Gene Expression Profiling

1 Jul 2005

Abstract excerpt

PURPOSE: Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is an increasingly identified precursor to infiltrating ductal adenocarcinoma. Although our knowledge of the clinical and pathologic features of IPMNs is increasing, the molecular mechanisms underlying these neoplasms remain poorly understood. EXPERIMENTAL DESIGNS: To provide further insight into the molecular pathobiology of IPMNs, global...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16000561
DOI: 10.1158/1078-0432.ccr-04-2471

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic Down-Regulation of <i>CDKN1C/p57KIP2</i> in Pancreatic Ductal Neoplasms Identified by Gene Expression ProfilingPMID 16000561Read ↗

Genome-Wide CpG Island Profiling of Intraductal Papillary Mucinous Neoplasms of the PancreasSemantic proximity Read ↗

CDKN1C/p57kip2is a candidate tumor suppressor gene in human breast cancerSemantic proximity Read ↗

Genome-Wide Analysis of Promoter Methylation Associated with Gene Expression Profile in Pancreatic AdenocarcinomaSemantic proximity Read ↗

Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreasSemantic proximity Read ↗

Epigenetic inactivation of IRX4 is responsible for acceleration of cell growth in human pancreatic cancerSemantic proximity Read ↗

Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15.Semantic proximity Read ↗

Differential effect of epigenetic alterations and genomic deletions of CDK inhibitors [<i>p16</i>(<i>INK4a</i>), <i>p15</i>(<i>INK4b</i>), <i>p14</i>(<i>ARF</i>)] in mantle cell lymphomaSemantic proximity Read ↗

Silencing of <i>CDKN1C</i> (<i>p57<sup>KIP2</sup> </i>) is associated with hypomethylation at KvDMR1 in Beckwith–Wiedemann syndromeSemantic proximity Read ↗

Human Pancreatic Carcinoma Cells Activate Maspin Expression Through Loss of Epigenetic ControlSemantic proximity Read ↗

Aberrant methylation of p57KIP2 gene in lung and breast cancers and malignant mesotheliomasSemantic proximity Read ↗

<i>PTEN</i> promoter is methylated in a proportion of invasive breast cancersSemantic proximity Read ↗

Imprinted tumor suppressor genes <i>ARHI</i> and <i>PEG3</i> are the most frequently down‐regulated in human ovarian cancers by loss of heterozygosity and promoter methylationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.