Article
Humoral response to p53 is associated with conserved domains II and IV mutations in human colorectal cancer: a case-control study in Taiwan.
Oncology reports - 1 Nov 2004
Wu Chi-Ming, Tang Reiping, Chen Jim-Ray, Wu Meng-Chih, Chien Huei-Tzu, Changchien Chung Rong, Hsieh Ling-Ling
Abstract excerpt
To explore the relationship between mutations of the p53 gene, p53 protein accumulation in tumor tissues and the presence of anti-p53 antibodies (Ab) in sera, a matched case-control study with 63 colorectal cancer patients positive for p53-Ab was carried out. These control patients were matched for age, gender, as well as tumor site and stage with 63 colorectal cancer patients positive for p53-Ab. The study was...
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