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Article

NOD2 3020insC alone is not sufficient for colorectal cancer predisposition.

Cancer research - 15 Oct 2004

Alhopuro Pia, Ahvenainen Taru, Mecklin Jukka-Pekka, Juhola Matti, Järvinen Heikki J, Karhu Auli, Aaltonen Lauri A

Abstract excerpt

Mutations in NOD2 have been shown to associate with increased susceptibility to Crohn's disease. A recent Polish study linked the truncating NOD2 3020insC variant with an increased risk of colorectal cancer (CRC) at an older age (>50 years) of disease onset, with an odds ratio of 2.23. We studied the possible contribution of the 3020insC variant to CRC risk in a series of 1,042 Finnish population-based patients...

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Identifiers

PMID: 15492242
DOI: 10.1158/0008-5472.CAN-04-2364

Genes

NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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NOD2 3020insC alone is not sufficient for colorectal cancer predisposition.PMID 15492242Read ↗

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