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The NOD2 3020insC mutation and the risk of colorectal cancer.

Cancer research - 1 Mar 2004

Kurzawski Grzegorz, Suchy Janina, Kładny Józef, Grabowska Ewa, Mierzejewski Marek, Jakubowska Anna, Debniak Tadeusz, Cybulski Cezary, Kowalska Elsbieta, Szych Zbigniew, Domagała Wenancjusz, Scott Rodney J, Lubiński Jan

Abstract excerpt

Several predispositions to colorectal cancer have been identified, but little is known about genetic susceptibilities to disease in older persons. Colorectal cancer is a risk in Crohn's disease and is believed to be associated with an inappropriate inflammatory response. Recently, the NOD2 gene has been associated with Crohn's disease, which further strengthens the notion that the inflammatory response plays a...

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Identifiers

PMID: 14996717
DOI: 10.1158/0008-5472.can-03-3791

Genes

NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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