Article
The 3020insC NOD2 gene mutation in patients with ovarian cancer.
Ginekologia polska - 1 Aug 2008
Magnowski Piotr, Medrek Krzysztof, Magnowska Magdalena, Stawicka Małgorzata, Kedzia Helena, Górski Bohdan, Lubiński Jan, Spaczyński Marek
Abstract excerpt
OBJECTIVE: There is an increasing evidence that genetic factors play a role in the etiology of malignant tumors. Mutations of BRCA1 and BRCA2 genes are responsible for an increased risk of ovarian cancer. The role of mutations in NOD2 gene in this type of neoplasm is still under investigation. THE AIM: The aim of this study was to determine: 1. incidence of NOD 2 3020insC constitutional mutation in a group of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.