Article
A Crohn's disease-associated insertion polymorphism (3020insC) in the NOD2 gene is not associated with psoriasis vulgaris, palmo-plantar pustular psoriasis or guttate psoriasis.
Experimental dermatology - 1 Aug 2003
Young C, Allen M H, Cuthbert A, Ameen M, Veal C, Leman J, Burden A D, Kirby B, Griffiths C E M, Trembath R C, Mathew C G, Barker J N W N
Abstract excerpt
A C-insertion polymorphism in the NOD2 gene (3020insC) on chromosome 16 is a rare mutation associated with Crohn's disease. Crohn's disease and psoriasis are more commonly observed together than expected by chance. Furthermore a susceptibility locus for psoriasis has been identified on chromosome 16q which overlaps the recently identified susceptibility locus for Crohn's disease. Thus, NOD2 may potentially be...
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