Article
Role of neuronal nicotinic receptors in the effects of nicotine and ethanol on contextual fear conditioning.
Neuroscience - 1 Jan 2004
Wehner J M, Keller J J, Keller A B, Picciotto M R, Paylor R, Booker T K, Beaudet A, Heinemann S F, Balogh S A
Abstract excerpt
Nicotine can enhance contextual learning while ethanol impairs some forms of learning. Nicotine can overcome some of the impairing effects of ethanol when the two drugs are co-administered. The specific brain nicotinic acetylcholine receptors (nAChRs) that mediate nicotine's effects on contextual learning and whether any of ethanol's actions are mediated by nAChRs are unknown. The potential roles of nAChRs in...
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