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Article

ZAK re-programs atrial natriuretic factor expression and induces hypertrophic growth in H9c2 cardiomyoblast cells.

Biochemical and biophysical research communications - 19 Nov 2004

Huang Chih-Yang, Chueh Pin Ju, Tseng Chien-Tang, Liu Kuan-Yu, Tsai Hsiao-Ya, Kuo Wei-Wen, Chou Ming-Yung, Yang Jaw-Ji

Abstract excerpt

Various intracellular or intercellular stimuli have been associated with the development of cardiac cell hypertrophy. However, the mechanisms underlying this association are not completely understood. In a previous study we determined that ZAK mRNA expression is abundant in heart. ZAK is a mitogen-activated protein kinase kinase kinase (MAP3K) that activates the stress-activated protein kinase/c-jun N-terminal...

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Identifiers

PMID: 15485649
DOI: 10.1016/j.bbrc.2004.09.156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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