Article
Cypher/ZASP is a novel A-kinase anchoring protein.
The Journal of biological chemistry - 11 Oct 2013
Lin Changsong, Guo Xiaogang, Lange Stephan, Liu Jie, Ouyang Kunfu, Yin Xiang, Jiang Liujun, Cai Yibo, Mu Yongxin, Sheikh Farah, Ye Sheng, Chen Ju, Ke Yuehai, Cheng Hongqiang
Abstract excerpt
PKA signaling is important for the post-translational modification of proteins, especially those in cardiomyocytes involved in cardiac excitation-contraction coupling. PKA activity is spatially and temporally regulated through compartmentalization by protein kinase A anchoring proteins. Cypher/ZASP, a member of PDZ-LIM domain protein family, is a cytoskeletal protein that forms multiprotein complexes at...
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