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Article

Interaction of fibronectin with human colon adenocarcinoma cells: effect on the in vivo tumorigenic capacity.

Oncology - 1 Jan 2002

López-Conejo M Teresa, Olmo Nieves, Turnay Javier, López De Silanes Isabel, Lizarbe M Antonia

Abstract excerpt

Fibronectin (FN) modulates the behavior of the poorly differentiated, human colon adenocarcinoma-derived BCS-TC2 cells by promoting adhesion through the alpha(5)beta(1)-integrin, as this effect is blocked by anti-alpha(5) and beta(1 )chain antibodies. BCS-TC2 cells are not tumorigenic in vivo, but are able to form tumors when coinjected with FN in nude mice. From these tumors, a tumorigenic cell subline...

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PMID: 12138246
DOI: 10.1159/000065070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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