Article
Comparative study of T84 and T84SF human colon carcinoma cells: in vitro and in vivo ultrastructural and functional characterization of cell culture and metastasis.
Virchows Archiv : an international journal of pathology - 1 Jul 2006
Alessandro Riccardo, Di Bella Maria Antonietta, Flugy Anna Maria, Fontana Simona, Damiani Francesca, Corrado Chiara, Colomba Paolo, Todaro Matilde, Russo Domenica, Santoro Alessandra, Kohn Elise C, De Leo Giacomo
Abstract excerpt
To better understand the relationship between tumor heterogeneity, differentiation, and metastasis, suitable experimental models permitting in vitro and in vivo studies are necessary. A new variant cell line (T84SF) exhibiting an altered phenotype was recently selected from a colon cancer cell line (T84) by repetitive plating on TNF-alpha treated human endothelial cells and subsequent selection for adherent...
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