Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model.

Oncogene - 7 Apr 2005

Minard Meghan E, Herynk Matthew H, Collard John G, Gallick Gary E

Abstract excerpt

Alterations in migration and adhesion are critical to invasion and metastasis. To examine signaling pathways important for colon tumor metastasis, cells of increased migratory potential from the low migratory SW480 human colorectal carcinoma parental cell line were biologically selected by serial migration through modified Boyden chambers. Several sublines were obtained with statistically significantly increased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma
Share to Cell Movement
Share to Colonic Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanine Nucleotide Exchange Factors

Share to Mice, Nude

Share to Neoplasm Metastasis

Share to Neoplasms, Experimental

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 15735692
DOI: 10.1038/sj.onc.1208503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model.PMID 15735692Read ↗

Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells.Semantic proximity Read ↗

Lentivirus-Mediated Silencing of Tiam1 Gene Influences Multiple Functions of a Human Colorectal Cancer Cell LineSemantic proximity Read ↗

Fascin, a Novel Target of β-Catenin-TCF Signaling, Is Expressed at the Invasive Front of Human Colon CancerSemantic proximity Read ↗

Alternative splicing of TIA‐1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistanceSemantic proximity Read ↗

TIAM1 promotes chemoresistance and tumor invasiveness in colorectal cancerSemantic proximity Read ↗

Dynamic cell culture modulates colon cancer cell migration in a novel 3D cell culture systemSemantic proximity Read ↗

Loss of KAI1 expression in the progression of colorectal cancer.Semantic proximity Read ↗

Identification and phenotypic characterization of a subpopulation of T84 human colon cancer cells, after selection on activated endothelial cells.Semantic proximity Read ↗

Reduction in gap junction intercellular communication promotes glioma migration.Semantic proximity Read ↗

<em>In vitro</em> Cell Migration and Invasion AssaysSemantic proximity Read ↗

Activation of c-Met in colorectal carcinoma cells leads to constitutive association of tyrosine-phosphorylated beta-catenin.Semantic proximity Read ↗

Downregulation of Rap1GAP in Human Tumor Cells Alters Cell/Matrix and Cell/Cell AdhesionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.