Article
Characterization of QTL with major effects on fatness and growth on mouse chromosome 2.
Obesity research - 1 Sept 2004
Jerez-Timaure Nancy C, Kearney Francis, Simpson E Barry, Eisen Eugene J, Pomp Daniel
Abstract excerpt
OBJECTIVE: To isolate and characterize a region on mouse chromosome 2 harboring quantitative trait loci with large influences on growth and fatness. RESEARCH METHODS AND PROCEDURES: A congenic line [M16i.B6-(D2Mit306-D2Mit52); MB2] was created using the polygenic obese M16i selection line as the recipient for an approximately 38-centimorgan region from C57BL/6J. Males and females from M16i and MB2 were compared...
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