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Article

Genetic variants of the mannan-binding lectin are associated with immune reactivity to mannans in Crohn's disease.

Gastroenterology - 1 Oct 2004

Seibold Frank, Konrad Astrid, Flogerzi Beatrice, Seibold-Schmid Beatrice, Arni Stephan, Jüliger Simone, Kun Jürgen F J

Abstract excerpt

BACKGROUND & AIMS: Some patients with Crohn's disease (CD) develop antibodies against mannan, a component of the yeast Saccharomyces cerevisiae cell wall. Mannan-binding lectin (MBL), a component of the innate immune system, can bind to S. cerevisiae . MBL concentration depends on genetic polymor...

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Identifiers

PMID: 15480986
DOI: 10.1053/j.gastro.2004.07.056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15480986-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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