Article
Novel anti-glycan antibodies related to inflammatory bowel disease diagnosis and phenotype.
The American journal of gastroenterology - 1 Jun 2009
Seow Cynthia H, Stempak Joanne M, Xu Wei, Lan Hui, Griffiths Anne M, Greenberg Gordon R, Steinhart A Hillary, Dotan Nir, Silverberg Mark S
Abstract excerpt
OBJECTIVES: We sought to evaluate whether two novel immunoglobulin A (IgA) cell wall polysaccharide antibodies, anti-laminarin (anti-L) and anti-chitin (anti-C), aid in the diagnosis and phenotype differentiation of Crohn's disease (CD) and ulcerative colitis (UC). METHODS: A cohort of 818 individuals with inflammatory bowel disease (IBD; 517 CD and 301 UC) from two IBD tertiary referral centers, with median ages...
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