Article
Structure and tropomyosin binding properties of the N-terminal capping domain of tropomodulin 1.
Biophysical journal - 1 Jan 2005
Greenfield Norma J, Kostyukova Alla S, Hitchcock-DeGregori Sarah E
Abstract excerpt
Two families of actin regulatory proteins are the tropomodulins and tropomyosins. Tropomodulin binds to tropomyosin (TM) and to the pointed end of actin filaments and "caps" the pointed end (i.e., inhibits its polymerization and depolymerization). Tropomodulin 1 has two distinct actin-capping reg...
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