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Article

Localization of the binding interface between leiomodin-2 and α-tropomyosin.

Biochimica et biophysica acta - 1 May 2016

Colpan Mert, Tolkatchev Dmitri, Grover Samantha, Helms Gregory L, Cort John R, Moroz Natalia, Kostyukova Alla S

Abstract excerpt

The development of some familial dilated cardiomyopathies (DCM) correlates with the presence of mutations in proteins that regulate the organization and function of thin filaments in cardiac muscle cells. Harmful effects of some mutations might be caused by disruption of yet uncharacterized protein-protein interactions. We used nuclear magnetic resonance spectroscopy to localize the region of striated muscle...

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Source

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Identifiers

PMID: 26873245
DOI: 10.1016/j.bbapap.2016.02.009
PMCID: PMC5079754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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