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Article

Induction of spine growth and synapse formation by regulation of the spine actin cytoskeleton.

Neuron - 14 Oct 2004

Zito Karen, Knott Graham, Shepherd Gordon M G, Shenolikar Shirish, Svoboda Karel

Abstract excerpt

We explored the relationship between regulation of the spine actin cytoskeleton, spine morphogenesis, and synapse formation by manipulating expression of the actin binding protein NrbI and its deletion mutants. In pyramidal neurons of cultured rat hippocampal slices, NrbI is concentrated in dendritic spines by binding to the actin cytoskeleton. Expression of one NrbI deletion mutant, containing the actin binding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15473970
DOI: 10.1016/j.neuron.2004.09.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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