Article
Quantitative and qualitative differences in proatherogenic NKT cells in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2004
Major Amy S, Wilson Michael T, McCaleb Jennifer L, Ru Su Yan, Stanic Aleksandar K, Joyce Sebastian, Van Kaer Luc, Fazio Sergio, Linton Macrae F
Abstract excerpt
BACKGROUND: Atherosclerosis is a disease marked by lipid accumulation and inflammation. Recently, atherosclerosis has gained recognition as an autoimmune-type syndrome characterized by increased activation of the innate and acquired immune systems. Natural killer T (NKT) cells have characteristics of both conventional T cells and NK cells and recognize glycolipid antigens presented in association with CD1d...
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