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Article

CYP17 genotype predicts serum hormone levels among pre-menopausal women.

Human reproduction (Oxford, England) - 1 Aug 2005

Small Chanley M, Marcus Michele, Sherman Stephanie L, Sullivan Amy K, Manatunga Amita K, Feigelson Heather Spencer

Abstract excerpt

BACKGROUND: CYP17, which encodes cytochrome P450c17alpha, mediates both steroid 17alpha-hydroxylase and 17,20-lyase activities, and is essential for the production of glucocorticoids and sex steroids. There is evidence that a common polymorphism in CYP17 (T27C) is associated with estrogen levels, making it a potential marker of disease risk. METHODS: This is the first study to examine the relationship between...

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Source

Identifiers

PMID: 15878919
DOI: 10.1093/humrep/dei054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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