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Article

CCR2-64I polymorphism and CCR5Delta32 deletion in patients with Alzheimer's disease.

Journal of the neurological sciences - 15 Oct 2004

Galimberti Daniela, Fenoglio Chiara, Lovati Carlo, Gatti Alberto, Guidi Ilaria, Venturelli Eliana, Cutter Gary R, Mariani Claudio, Forloni Gianluigi, Pettenati Carla, Baron Pierluigi, Conti Giancarlo, Bresolin Nereo, Scarpini Elio

Abstract excerpt

Monocyte chemoattractant protein-1 (MCP-1) and RANTES, as well as their related receptors, have been shown to be involved in Alzheimer's disease (AD) pathogenesis. Genes for their related receptors, CCR2 and CCR5, respectively, are characterized by the presence of two polymorphisms: a conservative change of a valine with an isoleucine at codon 64 of CCR2 (CCR2-64I) and a 32-bp deletion in the coding region of...

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Source

Identifiers

PMID: 15465089
DOI: 10.1016/j.jns.2004.07.005

Genes

CCR2
CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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