Article
Common CCR 5 polymorphism in stroke: the CCR 5 delta32 polymorphism differentiates cardioembolism from other aetiologies of ischaemic cerebrovascular diseases.
Scandinavian journal of immunology - 1 Nov 2009
Kostulas N, Nikolaos K, Markaki I, Ioanna M, Kostulas V, Vasilios K, Hillert J, Jan H, Kostulas K, Konstantinos K
Abstract excerpt
Inflammation is involved in the development of atherosclerosis. The CC chemokine receptor 5 (CCR5) initiates chemotaxis and modulates the inflammation secondary to atherosclerosis and related vascular diseases. The CCR5 Delta32 polymorphism influences the expression of CCR5 on the cell surface. The purpose of this study was to examine the effect of the Delta32 polymorphism in ischaemic cerebrovascular disease...
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