Article
The chemokine receptor CCR5 genetic polymorphism and expression in rheumatoid arthritis patients.
Scandinavian journal of rheumatology - 1 Jan 2000
Kohem C L, Brenol J C T, Xavier R M, Bredemeier M, Brenol C V, Dedavid e Silva T L, de Castilhos Mello A, Cañedo A D, Neves A G, Chies J A B
Abstract excerpt
OBJECTIVES: To identify the genetic polymorphism of the chemokine receptor CCR5 (the Delta32 allelic variant) in patients with rheumatoid arthritis (RA) and compare the findings with healthy controls. To compare the CCR5 phenotypic expression in T cells and monocytes isolated from the peripheral blood and synovial fluid in a subgroup of RA patients. METHODS: CCR5 genes of 92 RA patients and 160 healthy controls...
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