Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new statistical method for evaluation of L5178Ytk(+/-) mammalian cell mutation data using microwell method.

Mutation research - 27 May 2002

Omori Takashi, Honma Masamitsu, Hayashi Makoto, Honda Yoriko, Yoshimura Isao

Abstract excerpt

A statistical method to evaluate data from the mouse lymphoma L5178Y/tk assay (MLA) using microwell method is proposed. This proposed method is designed for data obtained from a single culture protocol instead of the duplicate culture recommended by United Kingdom Environmental Mutagen Society (UKEMS). The proposed method consists of the following three steps: (1) to apply Dunnett type test for identifying clear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Statistical

Share to Monte Carlo Method

Share to Mutagenicity Tests

Share to Reproducibility of Results

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 12034321
DOI: 10.1016/s1383-5718(02)00060-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new statistical method for evaluation of L5178Ytk(+/-) mammalian cell mutation data using microwell method.PMID 12034321Read ↗

In vitro mouse lymphoma (L5178Y Tk⁺/⁻-3.7.2C) forward mutation assay.Semantic proximity Read ↗

In Vitro Mouse Lymphoma Cell (L5178Y Tk+/- 3.7.2C) Forward Mutation Assay.Semantic proximity Read ↗

Mouse lymphoma thymidine kinase gene mutation assay: follow-up International Workshop on Genotoxicity Test Procedures, New Orleans, Louisiana, April 2000.Semantic proximity Read ↗

Can the L5178Y Tk+/- mouse lymphoma assay detect epigenetic silencing?Semantic proximity Read ↗

Mutant frequency in comparison to oxidative DNA damage induced by ochratoxin A in L5178Y tk+/- (3.7.2C) mouse lymphoma cells.Semantic proximity Read ↗

Mouse lymphoma thymidine kinase gene mutation assay: meeting of the International Workshop on Genotoxicity Testing, San Francisco, 2005, recommendations for 24-h treatment.Semantic proximity Read ↗

A method to distinguish between the de novo induction of thymidine kinase mutants and the selection of pre-existing thymidine kinase mutants in the mouse lymphoma assay.Semantic proximity Read ↗

[Thymidine kinase gene mutation assay--comparison of microwell method and soft agar method].Semantic proximity Read ↗

The mouse lymphoma assay.Semantic proximity Read ↗

The L5178Y/tk+/- mouse lymphoma specific gene and chromosomal mutation assay a phase III report of the U.S. Environmental Protection Agency Gene-Tox Program.Semantic proximity Read ↗

The IWGT in vitro Mammalian Cell Gene Mutation (MCGM) assays working group-Introductory remarks & consensus statements.Semantic proximity Read ↗

A compilation of two decades of mutagenicity test results with the Ames Salmonella typhimurium and L5178Y mouse lymphoma cell mutation assays.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.