Article
Linkage disequilibrium and haplotype tagging polymorphisms in the Tau H1 haplotype.
Neurogenetics - 1 Sept 2004
Oliveira Sofia A, Scott William K, Zhang Fengyu, Stajich Jeffrey M, Fujiwara Kenichiro, Hauser Michael, Scott Burton L, Pericak-Vance Margaret A, Vance Jeffery M, Martin Eden R
Abstract excerpt
We and others have previously detected association of the Tau H1 haplotype on chromosome 17 with risk of idiopathic Parkinson disease (PD). The H1 haplotype appears to have a fundamental importance in neurodegeneration, as multiple studies have shown it is also associated with an increased risk for progressive supranuclear palsy, corticobasal degeneration, frontotemporal lobar degeneration syndromes, and primary...
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