Article
The tau H1 haplotype is associated with Parkinson's disease in the Norwegian population.
Neuroscience letters - 5 Apr 2002
Farrer Matt, Skipper Lisa, Berg Marianne, Bisceglio Gina, Hanson Melissa, Hardy John, Adam Amanda, Gwinn-Hardy Katrina, Aasly Jan
Abstract excerpt
We investigated the association of Parkinson's disease (PD) with tau gene H1 haplotypes in the Norwegian population. In a sample of 96 unrelated PD cases and 68 control subjects, we observed an increased risk of PD for persons with the tau H1 haplotype (odds ratio=5.52; 95% confidence interval: 2.64-11.10; P=2.17x10(-6)). Findings provide evidence that tau participates in the PD pathogenic process and demonstrate...
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