Article
Role of the H1 haplotype of microtubule-associated protein tau (MAPT) gene in Greek patients with Parkinson's disease.
BMC neurology - 28 Jun 2009
Refenes Nikolaos, Bolbrinker Juliane, Tagaris Georgios, Orlacchio Antonio, Drakoulis Nikolaos, Kreutz Reinhold
Abstract excerpt
BACKGROUND: The extended tau haplotype (H1) that covers the entire human microtubule-associated protein tau (MAPT) gene has been implicated in Parkinson's disease (PD). Nevertheless, controversial results, such as two studies in Greek populations with opposite effects, have been reported. Therefore, we set out to determine whether the H1 haplotype and additional single nucleotide polymorphisms (SNPs) included in...
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