Article
Association between the extended tau haplotype and frontotemporal dementia.
Archives of neurology - 1 Jun 2002
Verpillat Patrice, Camuzat Agnès, Hannequin Didier, Thomas-Anterion Catherine, Puel Michèle, Belliard Serge, Dubois Bruno, Didic Mira, Michel Bernard-François, Lacomblez Lucette, Moreaud Olivier, Sellal François, Golfier Véronique, Campion Dominique, Clerget-Darpoux Françoise, Brice Alexis
Abstract excerpt
BACKGROUND: Recent studies have shown an association between an extended tau haplotype (H1) that covers the entire human tau gene and progressive supranuclear palsy or, more inconsistently, other neurodegenerative disorders, such as corticobasal degeneration, Parkinson disease, Alzheimer disease, and frontotemporal dementia (FTD). In addition, disease-causing mutations in the tau gene on chromosome 17 have been...
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