Article
The expression of lactate dehydrogenase is important for the cell cycle of Toxoplasma gondii.
The Journal of biological chemistry - 10 Dec 2004
Al-Anouti Fatme, Tomavo Stanislas, Parmley Stephen, Ananvoranich Sirinart
Abstract excerpt
In Toxoplasma gondii, lactate dehydrogenase is encoded by two independent and developmentally regulated genes LDH1 and LDH2. These genes and their products have been implicated in the control of a metabolic flux during parasite differentiation. To investigate the significance of LDH1 and LDH2 in this process, we generated stable transgenic parasite lines in which the expression of these two expressed isoforms of...
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