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Constitutive upregulation of transcription factors underlies permissive bradyzoite differentiation in a natural isolate of <i>Toxoplasma gondii</i>

2024-02-29

Abstract excerpt

Toxoplasma gondii bradyzoites play a critical role in pathology due to their long-term persistence in intermediate hosts and their potential to reactivate, resulting in severe diseases in immunocompromised individuals. Currently there is no effective treatment for eliminating bradyzoites. Hence, better in vitro models of T. gondii cyst development would facilitate identification of therapeutic targets for bradyz...

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Literature Corpus work
ebf637ad-9e32-5223-aa32-87e9bea59e74
DOI
10.1101/2024.02.28.582596
Open publication

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