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Article

Restriction Checkpoint Controls Bradyzoite Development in Toxoplasma gondii

2 Jun 2022

Abstract excerpt

Toxoplasma gondii is a virulent and abundant human pathogen that puts millions of silently infected people at risk of reactivation of the chronic disease. Encysted bradyzoites formed during the chronic stage are resistant to current therapies. Therefore, insights into the mechanism of tissue cyst formation and reactivation are major areas of investigation. The fact that rapidly dividing parasites differentiate...

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PMID: 35652638
DOI: 10.1128/spectrum.00702-22

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