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Differentiation of <i>Toxoplasma</i> into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligase

2025-07-30

Abstract excerpt

Toxoplasma and other Apicomplexan parasites, switch between different developmental stages to persist in and transmit between hosts. Toxoplasma can alternate between systemic tachyzoites and encysted bradyzoite forms found in the CNS and muscle tissues. How parasites sense these tissue types and trigger differentiation remains largely unknown. We show that Toxoplasma differentiation is induced under glucose-limi...

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Identifiers and source

Literature Corpus work
1cbe03cb-2c32-5581-a06d-b522e5b5c280
DOI
10.1101/2025.07.27.667068
Open publication

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Differentiation of <i>Toxoplasma</i> into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligaseDOI 10.1101/2025.07.27.667068
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