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Article

Phase variable desialylation of host proteins that bind to <i>Streptococcus pneumoniae in vivo</i> and protect the airway

3 Aug 2004

Abstract excerpt

Most clinical isolates of Streptococcus pneumoniae consist of heterogeneous populations of at least two colony phenotypes, opaque and transparent, selected for in the bloodstream and nasopharynx, respectively. Microarray analysis revealed 24 orfs that demonstrated differences in expression greater than twofold between variants of independent strains. Twenty-one of these showed increased expression in the...

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PMID: 15458413
DOI: 10.1111/j.1365-2958.2004.04252.x

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