Article
Identification of a pneumococcal glycosidase that modifies O-linked glycans.
Infection and immunity - 1 Apr 2009
Marion Carolyn, Limoli Dominique H, Bobulsky Gregory S, Abraham Jessica L, Burnaugh Amanda M, King Samantha J
Abstract excerpt
Colonization of the airway by Streptococcus pneumoniae is typically asymptomatic; however, progression of bacteria beyond the oronasopharynx can cause diseases including otitis media and pneumonia. The mechanisms by which S. pneumoniae establishes and maintains colonization remain poorly understood. Both N-linked and O-linked glycans are abundant in the airway. Our previous research demonstrated that S....
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