Article
Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families.
Arthritis and rheumatism - 1 Apr 2003
Jawaheer Damini, Seldin Michael F, Amos Christopher I, Chen Wei V, Shigeta Russell, Etzel Carol, Damle Aarti, Xiao Xiangli, Chen Dong, Lum Raymond F, Monteiro Joanita, Kern Marlene, Criswell Lindsey A, Albani Salvatore, Nelson J Lee, Clegg Daniel O, Pope Richard, Schroeder Harry W, Bridges S Louis, Pisetsky David S, Ward Ryk, Kastner Daniel L, Wilder Ronald L, Pincus Theodore, Callahan Leigh F, Flemming Donald, Wener Mark H, Gregersen Peter K
Abstract excerpt
OBJECTIVE: A number of non-HLA loci that have shown evidence (P < 0.05) for linkage with rheumatoid arthritis (RA) have been previously identified. The present study attempts to confirm these findings. METHODS: We performed a second genome-wide screen of 256 new multicase RA families recruited from across the United States by the North American Rheumatoid Arthritis Consortium. Affected sibling pair analysis on...
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