Article
Real-time quantitative PCR analysis of factor XI mRNA variants in human platelets.
Journal of thrombosis and haemostasis : JTH - 1 Oct 2004
Podmore A, Smith M, Savidge G, Alhaq A
Abstract excerpt
Coagulation factor XI (FXI) plays an essential role in blood coagulation. A deficiency of FXI is an unusual hemorrhagic diathesis in that the bleeding tendency can be highly variable, ranging from severe deficiencies with no symptoms to mild and moderate deficiencies requiring multiple blood transfusions for hemorrhages. This variability in bleeding has been attributed to a number of factors including the...
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