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Article

Evaluation of factor V mRNA to define the residual factor V expression levels in severe factor V deficiency.

Haematologica - 1 Mar 2008

Lunghi Barbara, Pinotti Mirko, Maestri Iva, Batorova Angelika, Bernardi Francesco

Abstract excerpt

We evaluated FV mRNA in severe factor V deficiency caused by the -12T/A IVS18 mutation, activating a cryptic splice site and leading to premature translation termination. Quantitative evaluation of factor V cDNA from homozygous and heterozygous subjects, and correction for nonsense mediated decay, suggested the presence of 0.1% of normal factor V mRNA.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18310546
DOI: 10.3324/haematol.11952

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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