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Article

Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease.

Neurogenetics - 1 Dec 2004

Nicodemus Kristin K, Stenger Judith E, Schmechel Donald E, Welsh-Bohmer Kathleen A, Saunders Ann M, Roses Allen D, Gilbert John R, Vance Jeffery M, Haines Jonathan L, Pericak-Vance Margaret A, Martin Eden R

Abstract excerpt

Several recent case-control studies have examined the association between single nucleotide polymorphisms (SNPs) in the promoter region of the apolipoprotein E gene (APOE) and risk of Alzheimer disease (AD), with conflicting results. We assessed the relation between five APOE region SNPs and risk of AD in both case-control and family-based analyses. We observed a statistically significant association with the...

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Source

Identifiers

PMID: 15455263
DOI: 10.1007/s10048-004-0189-9

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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