Article
Linkage/association study of a locus modulating total serum IgE on chromosome 14q13-24 in families with asthma.
Thorax - 1 Oct 2004
Mansur A H, Bishop D T, Holgate S T, Markham A F, Morrison J F J
Abstract excerpt
BACKGROUND: A study was undertaken to validate a locus modulating total serum IgE levels on 14q13-24. METHODS: A linkage and association study was performed between total serum IgE and a panel of seven microsatellites which map to the 14q13-24 region in 69 families with asthma recruited from Leeds, UK. RESULTS: Non-parametric, multipoint, sib pair analysis showed no evidence of genetic linkage between the...
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