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Article

Fine mapping of an IgE-controlling gene on chromosome 2q: Analysis of CTLA4 and CD28.

The Journal of allergy and clinical immunology - 1 Nov 2002

Howard Timothy D, Postma Dirkje S, Hawkins Gregory A, Koppelman Gerard H, Zheng Siqun L, Wysong Alicia K S, Xu Jianfeng, Meyers Deborah A, Bleecker Eugene R

Abstract excerpt

BACKGROUND: Several genomic regions have been identified that might contain genes contributing to the development of asthma and atopy. These include chromosome 2q33, where we have observed evidence for linkage for variation in total serum IgE levels in a Dutch asthma population. Two candidate genes, CTLA4 and CD28, important homeostatic regulators of T-cell activation and subsequent IgE production, map within...

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Source

Identifiers

PMID: 12417883
DOI: 10.1067/mai.2002.128723

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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