Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Few amino acid positions in rpoB are associated with most of the rifampin resistance in Mycobacterium tuberculosis.

BMC bioinformatics - 28 Sept 2004

Cummings Michael P, Segal Mark R

Abstract excerpt

BACKGROUND: Mutations in rpoB, the gene encoding the beta subunit of DNA-dependent RNA polymerase, are associated with rifampin resistance in Mycobacterium tuberculosis. Several studies have been conducted where minimum inhibitory concentration (MIC, which is defined as the minimum concentration of the antibiotic in a given culture medium below which bacterial growth is not inhibited) of rifampin has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acids
Share to Classification
Share to DNA-Directed RNA Polymerases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Microbial

Share to Models, Statistical

Share to Mycobacterium tuberculosis

Share to Regression Analysis

Share to Rifampin

Source

Open in PubMed Open full text

Identifiers

PMID: 15453919
DOI: 10.1186/1471-2105-5-137
PMCID: PMC524371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Few amino acid positions in rpoB are associated with most of the rifampin resistance in Mycobacterium tuberculosis.PMID 15453919Read ↗

rpoB Mutations and Effects on Rifampin Resistance in Mycobacterium tuberculosisSemantic proximity Read ↗

Rapid prediction of rifampin susceptibility of Mycobacterium tuberculosis.Semantic proximity Read ↗

rpoB Mutations are Associated with Variable Levels of Rifampin and Rifabutin Resistance in Mycobacterium tuberculosisSemantic proximity Read ↗

Identification of mutations in the rpoB encoding the RNA polymerase beta subunit in rifampicine-resistant Mycobacterium tuberculosis strains from Iran.Semantic proximity Read ↗

Rifampin resistance-associated mutations in the RIF resistance-determining region (RRDR) of the rpoB gene of Mycobacterium tuberculosis clinical isolates in Shanghai, ChinaSemantic proximity Read ↗

Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis.Semantic proximity Read ↗

Characterization of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis from eastern China.Semantic proximity Read ↗

Association between the rifampicin resistance mutations and rifabutin susceptibility in Mycobacterium tuberculosis: A meta-analysis.Semantic proximity Read ↗

Molecular analysis of codon 548 in the rpoB gene involved in Mycobacterium tuberculosis resistance to rifampin.Semantic proximity Read ↗

Genetic evaluation of relationship between mutations in rpoB and resistance of Mycobacterium tuberculosis to rifampin.Semantic proximity Read ↗

Relationship between rifampin MICs for and rpoB mutations of Mycobacterium tuberculosis strains isolated in JapanSemantic proximity Read ↗

Rifampin-resistance-associated mutations in the rifampin-resistance-determining region of the rpoB gene of Mycobacterium tuberculosis clinical isolates in Shanghai, PR China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.