Article
Characterization of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis from eastern China.
Journal of applied microbiology - 1 Sept 2008
Sheng J, Li J, Sheng G, Yu H, Huang H, Cao H, Lu Y, Deng X
Abstract excerpt
AIMS: The aim of this study was to investigate the features of rpoB gene mutations associated with Rifampin (RIF) resistance in Mycobacterium tuberculosis (M. tuberculosis) in eastern China. METHODS AND RESULTS: The mutations of rpoB gene in 56 clinical isolates of M. tuberculosis resisted to one to four first-line drugs (rifampin, isonicotinyl hydrazide, ethambutol and streptomycin) were analysed by polymerase...
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