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Article

Characterization of the sleep-wake patterns in mice lacking fatty acid amide hydrolase.

Sleep - 1 Aug 2004

Huitron-Resendiz Salvador, Sanchez-Alavez Manuel, Wills Derek N, Cravatt Benjamin F, Henriksen Steven J

Abstract excerpt

STUDY OBJECTIVES: Oleamide and anandamide are fatty acid amides implicated in the regulatory mechanisms of sleep processes. However, due to their prompt catabolism by fatty acid amide hydrolase (FAAH), their pharmacologic and behavioral effects, in vivo, disappear rapidly. To determine if, in the absence of FAAH, the hypnogenic fatty acid amides induce an increase of sleep, we characterized the sleep-wake patters...

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Source

Identifiers

PMID: 15453543
DOI: 10.1093/sleep/27.5.857

Genes

FAAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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